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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TTK
All Species:
25.45
Human Site:
S519
Identified Species:
46.67
UniProt:
P33981
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P33981
NP_003309.2
857
97072
S519
S
S
A
N
E
C
I
S
V
K
G
R
I
Y
S
Chimpanzee
Pan troglodytes
XP_001146752
857
97034
S519
S
S
A
N
E
C
I
S
V
K
G
R
I
Y
S
Rhesus Macaque
Macaca mulatta
XP_001111082
778
87619
C479
K
N
D
F
P
P
A
C
Q
L
S
T
P
Y
G
Dog
Lupus familis
XP_539016
855
96614
S516
S
S
T
N
E
C
I
S
V
K
G
R
M
Y
S
Cat
Felis silvestris
Mouse
Mus musculus
P35761
856
96192
S518
S
S
I
N
E
C
I
S
V
N
G
R
I
Y
S
Rat
Rattus norvegicus
NP_001101642
835
94323
S497
S
S
M
S
E
C
I
S
V
N
G
R
I
Y
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512474
935
104827
T530
F
S
S
N
E
C
I
T
V
K
G
R
M
Y
S
Chicken
Gallus gallus
XP_419867
879
99691
A536
I
P
S
N
E
C
I
A
V
K
G
R
I
Y
T
Frog
Xenopus laevis
NP_001082090
882
99060
V540
F
A
S
S
D
C
I
V
V
K
G
R
A
Y
A
Zebra Danio
Brachydanio rerio
Q8AYG3
982
109993
T647
A
F
S
N
E
S
I
T
I
K
G
K
Q
F
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002301009
818
91361
D506
N
N
I
I
Q
L
I
D
Y
E
V
T
D
K
A
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_565160
777
86358
N478
T
L
L
Q
E
V
L
N
G
T
M
S
N
K
D
Baker's Yeast
Sacchar. cerevisiae
P54199
764
86809
Y465
K
G
S
G
N
R
V
Y
A
L
K
R
V
S
F
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
85.7
87.4
N.A.
74.3
76.9
N.A.
64.2
61
52.8
41.4
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.6
87.7
92.6
N.A.
84.8
85.6
N.A.
73.6
74.5
68.4
57
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
6.6
86.6
N.A.
86.6
80
N.A.
73.3
66.6
46.6
33.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
13.3
93.3
N.A.
86.6
86.6
N.A.
93.3
86.6
80
73.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
23.1
N.A.
N.A.
22.9
22.7
N.A.
Protein Similarity:
40.2
N.A.
N.A.
42.3
44.5
N.A.
P-Site Identity:
6.6
N.A.
N.A.
6.6
6.6
N.A.
P-Site Similarity:
40
N.A.
N.A.
26.6
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
16
0
0
0
8
8
8
0
0
0
8
0
16
% A
% Cys:
0
0
0
0
0
62
0
8
0
0
0
0
0
0
0
% C
% Asp:
0
0
8
0
8
0
0
8
0
0
0
0
8
0
8
% D
% Glu:
0
0
0
0
70
0
0
0
0
8
0
0
0
0
0
% E
% Phe:
16
8
0
8
0
0
0
0
0
0
0
0
0
8
16
% F
% Gly:
0
8
0
8
0
0
0
0
8
0
70
0
0
0
8
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
8
0
16
8
0
0
77
0
8
0
0
0
39
0
0
% I
% Lys:
16
0
0
0
0
0
0
0
0
54
8
8
0
16
0
% K
% Leu:
0
8
8
0
0
8
8
0
0
16
0
0
0
0
0
% L
% Met:
0
0
8
0
0
0
0
0
0
0
8
0
16
0
0
% M
% Asn:
8
16
0
54
8
0
0
8
0
16
0
0
8
0
0
% N
% Pro:
0
8
0
0
8
8
0
0
0
0
0
0
8
0
0
% P
% Gln:
0
0
0
8
8
0
0
0
8
0
0
0
8
0
0
% Q
% Arg:
0
0
0
0
0
8
0
0
0
0
0
70
0
0
0
% R
% Ser:
39
47
39
16
0
8
0
39
0
0
8
8
0
8
47
% S
% Thr:
8
0
8
0
0
0
0
16
0
8
0
16
0
0
8
% T
% Val:
0
0
0
0
0
8
8
8
62
0
8
0
8
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
8
8
0
0
0
0
70
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _